Sakamoto M, Nagata Y, Furukawa A, Kusada T, Inamoto S, Senda T, Hirashima N, Suzuki R.

VAMP7 knockdown in secretory granules impairs CCL2 secretion in mast cells.

Biochem. Biophys. Res. Commun., 8:691:149258 (2023)

Nagata Y, Sasaki Y, Suzuki R.

Ephedrine Alkaloid-Independent High-Affinity Immunoglobulin-E Receptor (FcεRI) Internalization Results in CCL2 Production without Inducing Mast Cell Degranulation.

Biol. Pharm. Bull., 46:811-816 (2023)

Amma C, Inomata Y, Kohno R, Satake M, Furukawa A, Nagata Y, Sugiyama H, Seto T, Suzuki R.

Copper in airborne fine particulate matter (PM2.5) from urban sites causes the upregulation of pro-inflammatory cytokine IL-8 in human lung epithelial A549 cells.

Environ. Geochem. Health., 45(8):5879-5891 (2023)

Kohno R, Nagata Y, Ishihara T, Amma C, Inomata Y, Seto T, Suzuki R.

Benzo[a]pyrene induces NLRP1 expression and promotes prolonged inflammasome signaling.

Front. Immunol., 14:1154857 (2023)

Furukawa A, Shuchi Y, Wang J, Guillen-Poza PA, Ishizuka S, Kagoshima M, Ikeno R, Kumeta H, Yamasaki S, Matsumaru T, Saitoh T, Maenaka K.

Structural basis for plastic glycolipid recognition of C-type lectin Mincle.

Structure, 31:1077-108 (2023)

Tomita E, Kojima M, Nagashima Y, Tanaka K, Sugiyama H, Segawa Y, Furukawa A, Maenaka K, Maeda S, Yoshino T, Matsunaga S.

An Electron-Deficient CpE Iridium(III) Catalyst: Synthesis, Characterization, and Application to Ether-Directed C-H Amidation.

Angew Chem Int Ed Engl., 15;62:e202301259. (2023)

Fujisawa S, Nagata Y, Suzuki R Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor .

Cell. Immunol., 382:104632 (2022)

Mishima S, Sakamoto M, Kioka H, Nagata Y, Suzuki R
Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells
Front. Immunol., 13:885868 (2022)

Nagata Y, Suzuki R.
FcεRI: A Master Regulator of Mast Cell Functions
Cells, 11:622 (2022)

Selected as Feature Paper

Nagata Y, Suzuki R.
FcεRI Cluster Size Determines Effective Mast Cell Desensitization without Effector Responses in vitro

Int. Arch. Allergy Immunol., 1-9 (2021)
Selected as Editor’s Choice

Nagata Y, Ando H, Sasaki Y, Suzuki R.
Ephedra herb, Mao, inhibits antigen-induced mast cell degranulation by induction of the affinity receptor for IgE internalization

Pharmaceutical Res., 38:569-581 (2021)

Yamamoto T, Nagata Y, Hayashi S, Kadowaki M.
Isoflavones Suppress Cyp26b1 Expression in the Murine Colonic Lamina Propria

Biol Pharm Bull., 43:1945-1949 (2020)

Nagata Y, Yamamoto T, Kadowaki M.
Ginger Increases ALDH1A1 Expression and Enhances Retinoic Acid Signaling in a Human Colonic Epithelial Cell Line

J Nutr Sci Vitaminol (Tokyo), 66:462-467 (2020)

Suzuki R, Inoh Y, Yokawa S, Suzuki R, Furuno T, Hirashima N
Monomer hapten and hapten-specific IgG inhibit mast cell activation evoked by multivalent hapten with different mechanisms

Eur J Immunol., Dec;49:2172-2183 (2019)

Fujimura T, Lum SZC, Nagata Y, Kawamoto S, Oyoshi MK.
Influences of Maternal Factors Over Offspring Allergies and the Application for Food Allergy

Front Immunol., 23:1933 (2019)

Inoue Y., Hasegawa S., Miyachi K., Yamada T., Nakata S., Ipponjima S., Hibi T., Nemoto T., Tanaka M., Suzuki R., Hirashima N.
Development of 3D imaging technique of reconstructed human epidermis with immortalized human epidermal cell line

Exp. Dermatol., 27:563-570 (2018)

Suzuki R.
The Emerging Picture of Mast Cell Activation: The Complex Regulatory Network of High-Affinity Receptor for Immunoglobulin E Signaling.

Biol. Pharm. Bull., 40, 1828-1832 (2017)

Yokawa S., Suzuki T., Inouye S., Inoh Y, Suzuki R., Kanamori T., Furuno T., Hirashima N.
Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: identification of secretion sites in the intercellular contact regions.

Biochem. Biophys. Res. Commun., 485, 725-730 (2017)

Nagata Y, Yamamoto T, Hayashi M, Hayashi S, Kadowaki M.
Improvement of Therapeutic Efficacy of Oral Immunotherapy in　Combination with Regulatory T cell-Inducer Kakkonto in a Murine Food Allergy Model.

PLoS One., 12: e0170577 (2017)

Orakij W., Chetiyanukornkul T., Kasahara C., Boongla Y., Chuesaard T., Furuuchi M., Hata M., Tang N., Hayakawa K., Toriba A.,
Polycyclic aromatic hydrocarbons and their nitro-derivatives from indoor biomass fueled cooking in two rural areas of Thailand: a case study.

Air Qual. Atmos. Health in press (2017)

Hayakawa K., Tang N., Toriba A.
Recent analytical methods for atmospheric polycyclic aromatic hydrocarbons and their derivatives.

Biomed. Chromatogr., 31, e3862 (2017).

Tang N., Suzuki G., Morisaki H., Tokuda T., Yang X., Zhao L., Lin J., Kameda T., Toriba A., Hayakawa K.
Atmospheric behaviors of particulate-bound polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons in Beijing, China from 2004 to 2010.

Atmos. Environ., 152, 354-361 (2017)

Kakimoto K., Nagayoshi H., Konishi Y., Kajimura K., Ohura T., Nakano T., Hata M., Fruuchi M., Tang N., Hayakawa K., Toriba A.
Size Distribution of Chlorinated Polycyclic Aromatic Hydrocarbons in Atmospheric Particles

Arch. Environ. Contam. Toxicol., 72, 58-64 (2017).

Kakimoto Y., Takatori S., Okihashi M., Kajimura K., Toriba A., Hayakawa K.
Simple method for determination of fungicides in citrus fruits by liquid chromatography-tandem mass spectrometry.

Food Anal. Methods, 9, 3345-3351 (2016).

Yokawa S., Furuno T., Suzuki T., Inoh Y., Suzuki R., Hirashima N.
Effect of Cell Adhesion Molecule 1 Expression on Intracellular Granule Movement in Pancreatic α Cells.

Cell Biochem. Biophys., 74, 391-398 (2016)

Miller-Schulze JP., Paulsen M., Kameda T., Toriba A., Hayakawa K., Cassidy B., Naeher L., Villalobos MA., Simpson CD.
Nitro-PAH exposures of occupationally-exposed traffic workers and associated urinary 1-nitropyrene metabolite concentrations.

J. Environ. Sci., 49, 213-221 (2016).

Toriba A., Homma C., Kita M., Uozaki W., Boongla Y., Orakij W., Tang N., Kameda T., Hayakawa K.
Simultaneous determination of polycyclic aromatic hydrocarbon quinones by gas chromatography-tandem mass spectrometry, following a one-pot reductive trimethysilyl derivatization.

J. Chromatogr. A. 1459, 89-100 (2016).

Hayakawa K., Makino F., Yasuma M., Yoshita S., Chondo Y., Toriba A., Kameda T., Tang N., Kunugi M., Nakase H., Kinoshita C., Kawanishi T., Zhou Z., Qing W., Mishukov V., Tishchenko P., Lobanov V., Chizhova T., Koudryashova Y.
Polycyclic aromatic hydrocarbons in surface water of the Southeastern Japan Sea.

Chem. Pharm. Bull., 64, 625-631 (2016).

Kakimoto Y., Takatori S., Okihashi M., Kajimura K., Toriba A., Hayakawa K.
Simple method for determination of fungicides in citrus fruits by liquid chromatography-tandem mass spectrometry.

Food Anal. Methods, 1-7 (2016).

Kameda T., Azumi E., Fukushima A., Tang N., Matsuki A., Kamiya Y., Toriba A., Hayakawa K.
Mineral dust aerosols promote the formation of toxic nitropolycyclic aromatic compounds.

Sci. Rep., 6, 24427 (2016).

Kakimoto Y., Takatori S., Okihashi M., Kajimura K., Toriba A., Hayakawa K.
Simple method for determination of fungicides in citrus fruits by liquid chromatography-tandem mass spectrometry.

Food Anal. Methods, 1-7 (2016).

Coulibaly S., Minami H., Abe M., Furukawa N., Ono R., Hasei T., Toriba A., Tang N., Hayakawa K., Funasaka K., Asakawa D., Ikemori F., Watanabe M., Honda N., Wakabayashi K., Watanabe T.
Comparison of air pollution in metropolises in China (Beijing) and Japan (Osaka and Nagoya) on the basis of the levels of contaminants and mutagenicity.

Biol. Pharm Bull., 39, 415-422 (2016).

Morisaki H., Nakamura S., Tang N., Toriba A., Hayakawa K.
Benzo[c]fluorene in urban air: HPLC determination and mutagenic contribution relative to benzo[a]pyrene.

Anal. Sci., 32, 233-236 (2016).

Suzuki R., Scheffel J., Rivera J.
New Insights on the Signaling and Function of the High Affinity Receptor for IgE.

Curr. Top. Microbiol. Immunol., 388, 63-90 (2015)

Hirahara K., Onodera A., Villarino A., Bonelli M., Sciume` G., Laurence A, Sun H-W., Brooks SR., Vahedi G., Shih H-Y., Gutierrez-Cruz G., Iwata S., Suzuki R., Mikami Y., Okamoto Y., Nakayama T., Holland S., Hunter C.A., Kanno Y., O’Shea JJ.
Asymmetry of STAT action in driving IL-27 and IL-6 transcriptional outputs and cytokine specificity

Immunity, 42, 877-889 (2015)

Nagata Y, Yoshihisa Y, Kenji M, Rehman UM, Kitaichi N, Shimizu T.
Role of Macrophage Migration Inhibitory Factor (MIF) in Pollen-induced Allergic Conjunctivitis and Pollen Dermatitis in Mice.

PLoS One., 10: e0115593 (2015)

Pham CT., Tang N., Toriba A., Hayakawa K.
Polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in atmospheric particles and soil at a traffic site in Hanoi, Vietnam.

Polycycl. Aromat. Comp., 35, 355-371 (2015).

Kakimoto K., Nagayoshi H., Akutsu K., Konishi Y., Kajimura K., Hayakawa K., Toriba A.
Dechlorane Plus and decabromodiphenyl ether in atmospheric particles of northeast Asian cities. 12th IHPA Forum and selected studies on POPs

Environ. Sci. Pollut. Res., 22, 14600-14606 (2015).

Tang N., Hakamata M., Sato K., Okada Y., Yang X-Y., Tatematsu M., Toriba A., Kameda T., Hayakawa K.
Atmospheric behaviors of polycyclic aromatic hydrocarbons at a Japanese remote background site, Noto peninsula, from 2004 to 2014.

Atmos. Environ., 120, 144-151 (2015).

Kakimoto K., Nagayoshi H., Inazumi N., Tani A., Konishi Y., Kajimura K., Ohura T., Nakano T., Tang N., Hayakawa K., Toriba A.
Identification and characterization of oxidative metabolites of 1-chloropyrene.

Chem. Res. Toxicol., 28, 1728-1736 (2015).

Thongyen T., Hata M., Toriba A., Ikeda T., Koyama H., Otani Y., Furuuchi M.
Development of PM0.1 personalsampler for evaluation of personal exposure to aerosol nanoparticles.

Aerosol Air Qual. Res., 15, 180-187 (2015).

Suzuki R., Leach S., Liu W., Ralston E., Scheffel J., Zhang W., Lowell CA., Rivera J.
Molecular Editing of Cellular Responses by the High-Affinity Receptor for IgE.

Science, 343, 1021-1025 (2014)

Brochetta C #., Suzuki R #., (# Equal Contribution) Vita F., Soranzo MR., Claver J., Madjene LC., Vitte J., Varin-Blank N., Zabucchi G., Rivera J., Blank U.
Munc18-2 and Syntaxin 3 Control Distinct Essential Steps in Mast Cell Degranulation.

J. Immunol., 92, 41-51 (2014)

Dema B., Suzuki R., Rivera J.
Rethinking the role of immunoglobulin E and its high affinity receptor: New insights in allergy and beyond.

Int. Arch. of Allergy Immunol., 164, 271-279 (2014)

Ikeya M., Yamanoue K., Mochizuki Y., Konishi H., Tadokoro S., Tanaka M., Suzuki R., Hirashima N.
Orai-2 is localized on secretory granules and regulates antigen-evoked Ca2+ mobilization and exocytosis in mast cells.

Biochem. Biophys. Res. Commun., 451, 62-67 (2014)

Dema B., Charles N., Pellefigues C., Ricks TK., Suzuki R., Jiang C., Scheffel J., Hasni S., Hoffman V., Jablonski M., Sacre K., Golbert D, Papo T., Daugas E., Crampton S., Bolland S., Rivera J.
Immunoglobulin E Plays an Immune-Regulatory Role in Lupus.

J. Exp. Med., 211, 2159-2168 (2014)

Kakimoto K., Nagayoshi H., Konishi Y., Kajimura K., Ohura T., Hayakawa K., Toriba A.
Atmospheric chlorinated polycyclic aromatic hydrocarbons in East Asia.

Chemosphere, 111, 40-46 (2014).

Tang N., Sato K., Tokuda T., Tatematsu M., Hama H., Suematsu T., Kameda T., Toriba A., Hayakawa K.
Factors affecting atmospheric 1-, 2-nitropyrenes and 2-nitrofluoranthene in winter at Noto peninsula, a remote background site, Japan.

Chemosphere, 107, 324-330 (2014).

Chuesaard T., Chetiyanukornkul T., Kameda T., Hayakawa K., Toriba A.
Influence of biomass burning on the levels of atmospheric polycyclic aromatic hydrocarbons and their nitro derivatives in Chiang Mai, Thailand.

Aerosol Air Qual. Res., 14, 1247-1257 (2014).

Asahi M., Kawai M., Toyama T., Kumagai Y., Chuesaard T., Tang N., Kameda T., Hayakawa K., Toriba A.
Identification and quantification of in vivo metabolites of 9,10-phenanthrenequinone in human urine associated with producing reactive oxygen species.

Chem. Res. Toxicol., 27, 76-85 (2014).

Kakimoto K., Nagayoshi H., Takagi S., Akutsu K., Konishi Y., Kajimura K., Hayakawa K., Toriba A.
Inhalation and dietary exposure to Dechlorane Plus and polybrominated diphenyl ethers in Osaka, Japan.

Ecotoxicol. Environ. Saf., 99, 69-73 (2014).

Suzuki, R., Leach, S., Dema, B., Rivera, J.
Characterization of a phospho-specific antibody to the Fcε receptor γ chain reveals differences in the regulation of Syk and Akt phosphorylation.

Antibodies, 2, 321-337. (2013)

11) Dillahant SE., Sargent JL., Suzuki R., Rivera J., Olivera A.
Usage of SphK isoforms in mast cells is species and/or cell type determined.

J. Immunol., 190, 2058-2067. (2013)

Pham CT., Kameda T., Toriba A., Hayakawa K.
Polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in particulates emitted by motorcycles.

Envion. Pollutiton, 183, 175-183 (2013).

Chondo Y., Ying Li., Makino F., Tang N., Toriba A., Kameda T., Hayakawa K.
Determination of selected nitropolycyclic aromatic hydrocarbons in water samples.

Chem. Pharm. Bull., 61, 1269-1274 (2013).

Miller-Schulze JP., Paulsen M., Kameda T., Toriba A., Tang N., Tamura K., Dong L., Zhang X., Hayakawa K., Yost MG., Simpson CD.
Evaluation of urinary metabolites of 1-nitropyrene as biomarkers for exposure to diesel exhaust in taxi drivers of Shenyang, China.

J. Expo. Sci. Environ. Epidemiol., 23, 170-175 (2013).

Furuno T., Hagiyama M., Sekimura M., Okamoto K., Suzuki R., Ito A., Hirashima N., Nakanishi M.
Cell adhesion molecule 1 (CADM1) on mast cells promotes interaction with dorsal root ganglion neurites by heterophilic binding to nectin-3.

J. Neuroimmunol., 250, 50-58. (2012)

Sibilano R., Frossi B., Suzuki R., D’Inca` F., Gri G., Piconese S., Colombo MP., Rivera J. Pucillo CE.
Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA.

J Allergy and Clin Immunol., 130, 751-760. (2012)

Pullen NA., Barnstein BO., Falanga YT., Wang Z., Suzuki R., Lama Tamang TE., Khurana MC., Harry EA., Draber P., Bunting, KD., Mizuno K., Wilson BS., Ryan JJ.
Novel Mechanism for FcεRI-Mediated signal transducer and activator of transcription 5 (STAT5) Tyrosine Phosphorylation and the Selective Influence of STAT5B Over Mast Cell Cytokine Production.

J. Biol. Chem., 287, 2045-2054. (2012)

Hershko AH., Suzuki R., Charles N., Alvarez-Errico D., Sargent JL., Laurence A., Rivera J.
Mast Cell Interleukin-2 Production Controbutes to Suppression of Chronic Allergic Dermatitis.

Immunity, 35, 562－571. (2011)

Sibilano R., Gri G., Frossi B., Tripodo C., Suzuki R., Rivera J. Macdonald AS., Pucillo CE.
Soluble OX40 molecule mimics regulatory T cell modulatory activity on FcεRI-dependent mast cell degranulation.

J. Leukoc. Biol., 90, 831-838. (2011)

Carmi-Levy I., Motzik A., Ofir-Birin Y., Yagil Z., Yang CM., Kemeny DM., Min Han J., Kim S., Kay G., Nechushtan H., Suzuki R., Rivera J., Razin E.
Importin β Plays an Essential Role in the Regulation of the LysRS-Ap4A Pathway in Immunologically Activated Mast Cells.

Mol. Cell. Biol., 31, 2111-2121. (2011)

Suzuki R., Liu X., Olivera A., Aguiniga L., Yamashita Y., Blank U., Ambudkar IS., Rivera J.
Loss of TRPC1-mediated Ca2+ influx contributes to impaired mast cell degranulation and underlies the defective exocytotic response of Fyn-null mast cells.

J. Leukoc. Biol., 88, 863－875. (2010)

Alvarez-Errico D.#, Yamashita Y. #, Suzuki R., Odom S., Furumoto Y., Yamashita T., Rivera J.
Functional Analysis of Lyn Kinase A and B Isoforms Reveals Redundant and Distinct Roles in FcεRI-Dependent Mast Cell Activation.
#Authors contributions were equal. Editorials Highlighted Articles in The Journal of Immunol.

J. Immunol., 184, 5000-5008. (2010)

Yamashita T. #, Suzuki R. # (# equal contribution), Backlund PS., Yamashita Y., Yergey AL., Rivera J.
Differential dephosphorylation of the FcRγITAM tyrosines with dissimilar potential for activating Syk.

J. Biol. Chem., 283, 28584-28594. (2008)

Rivera J., Fierro NA., Olivera A., Suzuki R.
New Insights on Mast Cell Activation via the High Affinity Receptor for IgE.

Advances in Immunol., 98, 85-120. (2008)